Used primarily in research settings as a potent antagonist of the TRPV1 ion channel, which is involved in the regulation of pain and body temperature. It is widely applied in studies related to nociception and thermal sensitivity due to its ability to block capsaicin, heat, and proton activation of TRPV1. BCTC has also shown efficacy in preclinical models of inflammatory and neuropathic pain, making it a valuable tool compound for evaluating pain pathways and potential analgesic therapies. Additionally, it has been used to investigate cough reflexes, as TRPV1 plays a role in airway sensory signaling. Its selectivity and potency make it suitable for probing TRPV1 function in both in vitro and in vivo systems.