ACT-678689 is primarily used in research settings for its potential neuroprotective properties. It has shown activity in preclinical models related to neurodegenerative conditions, where it modulates specific neuronal signaling pathways involved in cell survival and inflammation. Its application extends to studies on cognitive function and synaptic plasticity, making it a candidate probe for investigating mechanisms in Alzheimer’s disease and other tauopathies. Due to its ability to cross the blood-brain barrier efficiently, ACT-678689 is valued in central nervous system drug development for evaluating target engagement and efficacy in vivo. It is not intended for clinical use and remains restricted to laboratory and experimental pharmacology.