Used as a selective antagonist for group II metabotropic glutamate receptors (mGluR2 and mGluR3) in neuroscience research. It helps in studying glutamatergic neurotransmission and synaptic plasticity. Commonly applied in experimental models to investigate the role of these receptors in neurological disorders such as epilepsy, schizophrenia, and anxiety. Also utilized in electrophysiological studies to modulate receptor activity and examine downstream signaling pathways in brain tissue.