(S)-MandelaMide is primarily utilized in the field of medicinal chemistry and drug development. It serves as a key intermediate in the synthesis of various biologically active compounds, particularly those targeting neurological disorders. Its chiral structure makes it valuable in the production of enantiomerically pure drugs, which are essential for achieving high specificity and efficacy in therapeutic applications. Additionally, it is employed in research focused on developing treatments for conditions such as Alzheimer's disease and Parkinson's disease, where precise molecular interactions are critical. Its role in asymmetric synthesis also extends to the creation of novel pharmaceuticals with improved pharmacokinetic properties.