(R)-Duloxetine is the R-enantiomer of duloxetine, a serotonin-norepinephrine reuptake inhibitor (SNRI). It is primarily used as a research chemical, chiral intermediate, reference standard, or building block in pharmaceutical synthesis and development. Note that the therapeutically active (S)-enantiomer is the active pharmaceutical ingredient in medications for major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic peripheral neuropathy, fibromyalgia, and stress urinary incontinence, where it balances serotonin and norepinephrine levels to alleviate symptoms of depression, anxiety, and chronic pain.