Zucapsaicin is primarily used in medical applications for its analgesic properties. It is commonly formulated in topical creams and gels to alleviate pain associated with conditions like osteoarthritis and neuropathic pain. By targeting the TRPV1 receptors in the skin, it helps reduce the sensation of pain and inflammation. It is often preferred for patients who require localized pain relief without systemic side effects. Additionally, it is used in research to study pain mechanisms and develop new therapeutic approaches for chronic pain management.