(S)-2-Morpholin-4-yl-propionic acid hydrochloride is primarily utilized in the field of organic synthesis as a chiral building block. It is often employed in the preparation of pharmaceutical compounds, particularly those requiring specific stereochemistry for biological activity. The morpholine ring and carboxylic acid group make it a versatile intermediate in the synthesis of various drugs, including those targeting the central nervous system. Additionally, it is used in the development of ligands for asymmetric catalysis, aiding in the production of enantiomerically pure substances. Its hydrochloride form enhances solubility, facilitating its use in aqueous reaction conditions.