(R)-Pyrrolidine-3-carboxylic acid hydrochloride is primarily utilized in pharmaceutical research and development. It serves as a key intermediate in the synthesis of various bioactive compounds, particularly those targeting neurological and psychiatric disorders. Its chiral structure makes it valuable in the production of enantiomerically pure drugs, enhancing their efficacy and reducing side effects. Additionally, it is employed in the development of peptidomimetics, which are used to mimic the structure and function of peptides in drug design. This compound is also explored in the creation of small molecule inhibitors for enzymes and receptors, contributing to advancements in therapeutic treatments for conditions like Alzheimer's disease, depression, and Parkinson's disease.