1-(3-(Trifluoromethyl)Phenyl)CyclopropanecarboxylicAcid
98%
Reagent
Code: #244154
CAS Number
104173-41-3
blur_circular Chemical Specifications
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Molecular Information
Weight
230.18 g/mol
Formula
C₁₁H₉F₃O₂
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) active compounds. Its structure allows for modulation of biological activity in drug candidates, especially in the design of antidepressants and antipsychotics. The trifluoromethyl group enhances metabolic stability and lipophilicity, improving blood-brain barrier penetration. Also employed in agrochemicals for creating bioactive molecules with improved environmental stability. Commonly utilized in medicinal chemistry research for structure-activity relationship (SAR) studies due to its rigid cyclopropane ring and electron-withdrawing substituent.
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