(1-(4-(Trifluoromethyl)phenyl)cyclopropyl)methanamine
98%
Reagent
Code: #243600
CAS Number
886365-83-9
blur_circular Chemical Specifications
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Molecular Information
Weight
215.21 g/mol
Formula
C₁₁H₁₂F₃N
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Registry Numbers
MDL Number
MFCD07374426
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its rigid cyclopropyl structure and electron-withdrawing trifluoromethyl group enhance metabolic stability and binding selectivity, making it valuable in designing serotonin and dopamine modulators. Commonly employed in the preparation of antidepressants and antipsychotics where improved bioavailability and blood-brain barrier penetration are required. Also explored in agrochemicals for its ability to improve compound lipophilicity and resistance to degradation.
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