Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its rigid cyclopropane structure with defined stereochemistry makes it valuable for constructing chiral building blocks in drug design. Commonly employed in the preparation of serotonin and norepinephrine reuptake inhibitors, where the trans configuration enhances binding selectivity to neurotransmitter transporters. Also utilized in the research of analgesic and antidepressant molecules due to its ability to influence metabolic stability and bioavailability when incorporated into larger molecular frameworks.