Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) with central nervous system activity. It serves in the preparation of selective enzyme inhibitors and receptor modulators due to the electron-withdrawing nature of the trifluoromethyl group, which enhances metabolic stability and binding affinity. Commonly employed in research settings for constructing complex organic molecules, especially in medicinal chemistry for antidepressants, antipsychotics, and anti-inflammatory agents. Its rigid indanone scaffold provides structural stability, making it valuable in optimizing drug candidates for improved pharmacokinetic properties.