Used primarily in the treatment of major depressive disorder, the compound demonstrates atypical antidepressant properties by modulating serotonin reuptake, though its mechanism differs from conventional SSRIs or SNRIs. It has shown efficacy in alleviating symptoms of depression, anxiety, and mood disturbances in clinical settings. Some studies suggest benefits in managing neuropathic pain and irritable bowel syndrome due to its effects on central nervous system pathways. It has also been explored for off-label use in cognitive enhancement and opioid withdrawal mitigation, though such uses carry risk of misuse. Due to potential for dependence and abuse, its therapeutic application is closely regulated in many countries.