diethyl((1S,2S)-2-((3,5-bis(trifluoromethyl)benzyl)amino)cyclohexyl)phosphoramidate
97%
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description Product Description
This chiral phosphoramidate, featuring a (1S,2S)-2-((3,5-bis(trifluoromethyl)benzyl)amino)cyclohexyl core, serves as a key intermediate in the synthesis of biologically active compounds, particularly pharmaceuticals targeting neurological and psychiatric disorders. The specific (S,S)-configuration and trifluoromethyl substituents provide enhanced metabolic stability, chiral selectivity, and improved target binding affinity, making it valuable in asymmetric synthesis for drug candidates. It is commonly used in medicinal chemistry to optimize pharmacokinetic properties and is essential in preparing enzyme inhibitors, where the phosphoramidate moiety enables mechanism-based inhibition.
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