diethyl((1S,2S)-2-((3,5-bis(trifluoromethyl)benzyl)amino)cyclohexyl)phosphoramidate

97%

Reagent Code: #233688

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 476.40 g/mol
Formula C₁₉H₂₇F₆N₂O₃P
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

This chiral phosphoramidate, featuring a (1S,2S)-2-((3,5-bis(trifluoromethyl)benzyl)amino)cyclohexyl core, serves as a key intermediate in the synthesis of biologically active compounds, particularly pharmaceuticals targeting neurological and psychiatric disorders. The specific (S,S)-configuration and trifluoromethyl substituents provide enhanced metabolic stability, chiral selectivity, and improved target binding affinity, making it valuable in asymmetric synthesis for drug candidates. It is commonly used in medicinal chemistry to optimize pharmacokinetic properties and is essential in preparing enzyme inhibitors, where the phosphoramidate moiety enables mechanism-based inhibition.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿32,300.00

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diethyl((1S,2S)-2-((3,5-bis(trifluoromethyl)benzyl)amino)cyclohexyl)phosphoramidate
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This chiral phosphoramidate, featuring a (1S,2S)-2-((3,5-bis(trifluoromethyl)benzyl)amino)cyclohexyl core, serves as a key intermediate in the synthesis of biologically active compounds, particularly pharmaceuticals targeting neurological and psychiatric disorders. The specific (S,S)-configuration and trifluoromethyl substituents provide enhanced metabolic stability, chiral selectivity, and improved target binding affinity, making it valuable in asymmetric synthesis for drug candidates. It is commonly us

This chiral phosphoramidate, featuring a (1S,2S)-2-((3,5-bis(trifluoromethyl)benzyl)amino)cyclohexyl core, serves as a key intermediate in the synthesis of biologically active compounds, particularly pharmaceuticals targeting neurological and psychiatric disorders. The specific (S,S)-configuration and trifluoromethyl substituents provide enhanced metabolic stability, chiral selectivity, and improved target binding affinity, making it valuable in asymmetric synthesis for drug candidates. It is commonly used in medicinal chemistry to optimize pharmacokinetic properties and is essential in preparing enzyme inhibitors, where the phosphoramidate moiety enables mechanism-based inhibition.

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