8-Amino-1-(trifluoromethyl)-1,2,3,5,6,7-hexahydro-s-indacen-1-ol
97%
Reagent
Code: #233327
CAS Number
2676863-22-0
science Other reagents with same CAS 2676863-22-0
blur_circular Chemical Specifications
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Molecular Information
Weight
257.25 g/mol
Formula
C₁₃H₁₄F₃NO
thermostat
Physical Properties
Boiling Point
353.0±42.0 °C(Predicted)
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Storage & Handling
Density
1.442±0.06 g/cm3(Predicted)
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of selective serotonin reuptake inhibitors (SSRIs), particularly in the production of antidepressant pharmaceuticals. Its unique trifluoromethyl and amino-hydroxy functionality enables enhanced binding affinity to neurotransmitter transporters, improving the potency and metabolic stability of the final drug compound. It is also employed in the development of neuroimaging agents due to its ability to cross the blood-brain barrier efficiently. Additionally, this compound serves as a building block in medicinal chemistry for designing novel CNS-active agents with optimized pharmacokinetic profiles.
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