(R)-N-((S)-1,3-Dihydrospiro[indene-2,4'-piperidin]-1-yl)-2-methylpropane-2-sulfinamide

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Reagent Code: #230959
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CAS Number 2245085-41-8

science Other reagents with same CAS 2245085-41-8

blur_circular Chemical Specifications

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Weight 306.47 g/mol
Formula C₁₇H₂₆N₂OS
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

This compound is a chiral N-sulfinyl protected amine intermediate, featuring a (R)-tert-butanesulfinamide group attached to the (S)-1-position of 1,3-dihydrospiro[indene-2,4'-piperidine]. It is used in asymmetric synthesis for the preparation of enantiomerically pure spirocyclic amines, particularly in pharmaceutical development targeting CNS or other therapeutic areas requiring high stereochemical control. The sulfinamide protecting group ensures stability during synthetic manipulations and can be readily removed under mild acidic conditions to yield the free amine with retained enantiopurity. This makes it valuable as an advanced intermediate in multi-step routes toward active pharmaceutical ingredients (APIs) with specific stereoisomers for optimal biological activity.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿5,480.00
inventory 250mg
10-20 days ฿13,240.00
inventory 1g
10-20 days ฿46,330.00

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(R)-N-((S)-1,3-Dihydrospiro[indene-2,4'-piperidin]-1-yl)-2-methylpropane-2-sulfinamide
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This compound is a chiral N-sulfinyl protected amine intermediate, featuring a (R)-tert-butanesulfinamide group attached to the (S)-1-position of 1,3-dihydrospiro[indene-2,4'-piperidine]. It is used in asymmetric synthesis for the preparation of enantiomerically pure spirocyclic amines, particularly in pharmaceutical development targeting CNS or other therapeutic areas requiring high stereochemical control. The sulfinamide protecting group ensures stability during synthetic manipulations and can be readily
This compound is a chiral N-sulfinyl protected amine intermediate, featuring a (R)-tert-butanesulfinamide group attached to the (S)-1-position of 1,3-dihydrospiro[indene-2,4'-piperidine]. It is used in asymmetric synthesis for the preparation of enantiomerically pure spirocyclic amines, particularly in pharmaceutical development targeting CNS or other therapeutic areas requiring high stereochemical control. The sulfinamide protecting group ensures stability during synthetic manipulations and can be readily removed under mild acidic conditions to yield the free amine with retained enantiopurity. This makes it valuable as an advanced intermediate in multi-step routes toward active pharmaceutical ingredients (APIs) with specific stereoisomers for optimal biological activity.
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