(R)-N-((S)-1,3-Dihydrospiro[indene-2,4'-piperidin]-1-yl)-2-methylpropane-2-sulfinamide
97%
Reagent
Code: #230959
CAS Number
2245085-41-8
science Other reagents with same CAS 2245085-41-8
blur_circular Chemical Specifications
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Molecular Information
Weight
306.47 g/mol
Formula
C₁₇H₂₆N₂OS
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
This compound is a chiral N-sulfinyl protected amine intermediate, featuring a (R)-tert-butanesulfinamide group attached to the (S)-1-position of 1,3-dihydrospiro[indene-2,4'-piperidine]. It is used in asymmetric synthesis for the preparation of enantiomerically pure spirocyclic amines, particularly in pharmaceutical development targeting CNS or other therapeutic areas requiring high stereochemical control. The sulfinamide protecting group ensures stability during synthetic manipulations and can be readily removed under mild acidic conditions to yield the free amine with retained enantiopurity. This makes it valuable as an advanced intermediate in multi-step routes toward active pharmaceutical ingredients (APIs) with specific stereoisomers for optimal biological activity.
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