tert-Butyl (3R,4S)-4-fluoro-3-hydroxypiperidine-1-carboxylate
98%
Reagent
Code: #229322
CAS Number
2306248-33-7
science Other reagents with same CAS 2306248-33-7
blur_circular Chemical Specifications
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Molecular Information
Weight
219.25 g/mol
Formula
C₁₀H₁₈FNO₃
thermostat
Physical Properties
Boiling Point
300.8±42.0 °C(Predicted)
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Storage & Handling
Density
1.15±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated piperidine-containing drugs. Its stereochemistry makes it valuable for constructing bioactive molecules with high enantioselectivity. Commonly employed in the production of central nervous system agents, including antidepressants and antipsychotics, due to the enhanced metabolic stability and binding affinity provided by the fluorine atom. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidates.
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