Used in pharmaceutical research as a building block for drug discovery, particularly in the development of bioisosteres to replace phenyl or other aromatic rings. Its rigid bicyclic structure helps improve metabolic stability, solubility, and binding selectivity in medicinal compounds. Commonly employed in the synthesis of CNS agents, kinase inhibitors, and PET tracers due to its favorable physicochemical properties and ability to modulate molecular conformation. Also utilized in structure-activity relationship (SAR) studies to enhance potency and reduce off-target effects.