Dantrolene sodium salt
10mM in DMSO
Reagent
Code: #168957
CAS Number
14663-23-1
science Other reagents with same CAS 14663-23-1
blur_circular Chemical Specifications
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Molecular Information
Weight
336.23 g/mol
Formula
C₁₄H₉N₄NaO₅
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Registry Numbers
MDL Number
MFCD00079130
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily to treat malignant hyperthermia, a life-threatening condition triggered by certain anesthetics that causes rapid rise in body temperature and muscle rigidity. It works by preventing excessive calcium release from the sarcoplasmic reticulum in muscle cells, thereby reducing muscle contraction and heat production. Administered intravenously during acute episodes, it is the only specific treatment for this condition. Also used orally in some cases to manage chronic muscle spasticity due to neurological disorders such as spinal cord injury or cerebral palsy. Its role is limited by potential hepatotoxicity with long-term use.
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