(−)-Voacangarine is a natural alkaloid found in plants of the Apocynaceae family, particularly the Voacanga genus. Used primarily in pharmacological research due to its complex alkaloid structure, which shows potential in studying neurological pathways and as an anti-cancer agent by potentially inhibiting cancer cell growth. It has been investigated for its effects on the central nervous system, particularly in modulating receptor activity that could influence mood and cognitive functions. Additionally, its unique chemical properties make it a candidate for the development of novel therapeutic agents, especially in the treatment of disorders related to neurotransmitter dysregulation. Researchers also explore its use in synthesizing other bioactive compounds, leveraging its intricate molecular framework for creating derivatives with enhanced or targeted biological activity. However, studies are still experimental and require further research to confirm efficacy and safety for human use.