Lodelaben is primarily used in the field of medical research, particularly in studies related to Alzheimer's disease. It functions as a gamma-secretase inhibitor, which plays a crucial role in modulating the production of amyloid-beta peptides. These peptides are known to accumulate in the brains of Alzheimer's patients, forming plaques that are associated with the progression of the disease. By inhibiting gamma-secretase, Lodelaben helps researchers investigate the mechanisms of amyloid-beta production and its impact on neurodegenerative processes. This makes it a valuable tool for developing potential therapeutic strategies aimed at reducing amyloid plaque formation and slowing the progression of Alzheimer's disease. Additionally, its use in experimental models contributes to a better understanding of the biochemical pathways involved in neurodegeneration.