2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol
96%
Reagent
Code: #231210
CAS Number
150026-75-8
blur_circular Chemical Specifications
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Molecular Information
Weight
457.99 g/mol
Formula
C₂₉H₂₈ClNO₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used in research as a fluorescent probe for studying amyloid-beta plaques in the brain, particularly in the context of Alzheimer's disease. Its structure allows it to bind selectively to amyloid aggregates, making it useful in imaging and diagnostic applications. It has been employed in positron emission tomography (PET) when labeled with radioactive isotopes, enabling non-invasive visualization of plaque deposition in living tissue. Also utilized in histological staining to detect amyloid in post-mortem brain samples. Shows potential in drug development for monitoring therapeutic efficacy in neurodegenerative disease models.
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