Used in biomedical research for near-infrared fluorescence imaging, particularly in the detection and monitoring of amyloid-beta aggregates associated with Alzheimer's disease. Its ability to cross the blood-brain barrier makes it valuable for non-invasive brain imaging in animal models. Also employed in studies focused on neuroinflammation due to its reactivity with reactive oxygen species. Suitable for in vivo imaging applications because of its high selectivity and low background interference.