AK-7
10mM in DMSO
Reagent
Code: #134427
CAS Number
420831-40-9
blur_circular Chemical Specifications
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Molecular Information
Weight
437.35 g/mol
Formula
C₁₉H₂₁BrN₂O₃S
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Storage & Handling
Storage
-20°C
description Product Description
AK-7 is primarily used in research settings for its potential neuroprotective properties. It acts as a selective inhibitor of sirtuin 2 (SIRT2), a protein involved in cellular aging and neurodegeneration. Due to this inhibitory action, AK-7 has shown promise in preclinical studies for the treatment of neurodegenerative diseases such as Huntington’s disease and Parkinson’s disease. It helps reduce neuroinflammation, improves motor function, and extends survival in animal models. Its ability to cross the blood-brain barrier enhances its utility in central nervous system research. AK-7 is not used clinically but remains a valuable tool compound for studying SIRT2-related pathways and developing future therapeutics for neurodegenerative conditions.
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