Periplocoside M is primarily studied for its potent insecticidal and antifeedant properties. It acts as a natural pesticide by disrupting the feeding behavior of certain insect pests, making it valuable in agricultural pest management. It has shown effectiveness against pests such as aphids and mites without causing significant harm to non-target organisms, suggesting potential for eco-friendly crop protection solutions. Research also indicates possible anti-inflammatory and immunomodulatory effects, opening avenues for its use in pharmaceutical development. Due to its bioactivity and natural origin, it is considered a candidate for green pesticide formulations and further pharmacological studies.