Nimbin is primarily known for its bioactive properties and finds application in traditional and modern medicinal systems. It exhibits anti-inflammatory, antipyretic, and analgesic effects, making it useful in formulations aimed at reducing fever and inflammation. Due to its antiviral activity, nimbin is studied for its potential in inhibiting certain viruses, including those causing skin infections. It also shows promise in dermatological applications, such as in the treatment of acne and eczema, owing to its antibacterial and anti-inflammatory actions. Additionally, ongoing research explores its antifungal properties and potential role in anticancer drug development.

In agriculture, nimbin acts as a natural pesticide. It helps protect crops from insect pests and fungal infections, offering an eco-friendly alternative to synthetic agrochemicals. Its biodegradable nature reduces environmental toxicity, supporting sustainable farming practices, particularly in organic agriculture.

Furthermore, nimbin is explored in cosmetic and personal care products for its skin-soothing and healing properties. It is incorporated into creams, ointments, herbal formulations, and hair care items like shampoos targeting skin health, minor wound repair, acne reduction, dandruff control, and prevention of scalp inflammation.