2-Methyl-[1,8]naphthyridine is primarily utilized in the field of medicinal chemistry and pharmaceutical research due to its structural properties, which make it a valuable scaffold for drug development. It serves as a key intermediate in the synthesis of various biologically active compounds, particularly those targeting enzymes and receptors involved in diseases. Its naphthyridine core is often incorporated into molecules designed for antimicrobial, antiviral, and anticancer applications. Additionally, it is explored in the development of fluorescent probes and sensors, leveraging its ability to interact with specific biological targets or metal ions. The compound’s versatility also extends to material science, where it is used in the design of organic electronic materials and coordination complexes.