Nampt-IN-1 is primarily used in research settings to study the role of nicotinamide phosphoribosyltransferase (NAMPT) in cellular processes. It is a potent inhibitor of NAMPT, an enzyme crucial for the biosynthesis of NAD+, a coenzyme involved in various metabolic reactions. By inhibiting NAMPT, this compound helps researchers investigate the effects of reduced NAD+ levels on cell viability, energy metabolism, and stress responses. It is particularly valuable in cancer research, as NAMPT inhibition can suppress tumor growth by targeting the metabolic pathways cancer cells rely on. Additionally, it is used to explore potential therapeutic strategies for diseases linked to NAD+ dysregulation, such as neurodegenerative disorders and metabolic syndromes.