VAS2870 is primarily utilized in research settings as a potent and selective inhibitor of NADPH oxidase (NOX) enzymes. Its application is significant in studying the role of reactive oxygen species (ROS) in various cellular processes and disease mechanisms. Researchers employ VAS2870 to investigate oxidative stress-related conditions, such as cardiovascular diseases, inflammation, and neurodegenerative disorders. By inhibiting NOX enzymes, it helps elucidate their contribution to pathological states and potential therapeutic targets. Additionally, VAS2870 is used in experimental models to explore the impact of ROS on cell signaling pathways, apoptosis, and tissue damage, providing insights into the development of antioxidant-based treatments.