VU 0361737 is used in neuroscience studies and research to investigate the role of the mGlu4 receptor in the nervous system, particularly in research on neurological disorders such as Parkinson's disease. It acts as a selective positive allosteric modulator of the mGlu4 receptor, which may help improve communication between neurons and alleviate disease symptoms. Additionally, studies are evaluating the potential of this compound for treating anxiety disorders and depression, with a focus on its impact on glutamate system function in the brain.