2-(4,7,10-Tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid
98%
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Used primarily in the synthesis of MRI contrast agents, this compound serves as a key chelating agent for binding gadolinium(III) and other metal ions. Its macrocyclic structure provides high stability and selectivity, reducing the risk of metal ion release in biological systems. It is especially valuable in developing targeted imaging agents due to the presence of a reactive acetic acid side chain, which can be easily conjugated to biomolecules such as peptides or antibodies. The tert-butoxycarbonyl (Boc) groups act as protecting groups, allowing for controlled deprotection and further functionalization during multi-step syntheses. Commonly employed in radiopharmaceutical and diagnostic research, it enables the creation of safer, more effective imaging probes.
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