Used in cancer therapy to inhibit tumor angiogenesis by targeting the VEGFR1 receptor, thereby blocking blood vessel formation that supports tumor growth. Employed in research and development of biologics for oncology, particularly in studies involving signal transduction pathways related to vascular endothelial growth factors. Serves as a reference standard in antibody characterization, potency assays, and biosimilar development. Also utilized in preclinical models to evaluate anti-angiogenic efficacy and mechanism of action.