Used in the treatment of various angiogenesis-related diseases, particularly in ophthalmology and oncology. It inhibits vascular endothelial growth factor (VEGF), thereby preventing the formation of new blood vessels that support tumor growth or contribute to retinal disorders. Commonly applied in therapies for age-related macular degeneration (AMD), diabetic retinopathy, and macular edema by reducing abnormal blood vessel growth and leakage in the retina. Also utilized in cancer treatment to suppress tumor angiogenesis, limiting the blood supply to tumors and slowing their progression. Its high specificity and binding affinity make it a valuable reference in biosimilar development and preclinical research for anti-angiogenic drugs.