Used in the treatment of autoimmune diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis. It works by binding to tumor necrosis factor-alpha (TNF-α), a key mediator of inflammation, and neutralizing its biological activity. This reduces inflammation, alleviates symptoms, slows down disease progression, and improves quality of life. It is administered intravenously and is often prescribed when other treatments have failed. Also used in research settings as a reference antibody for assay development and bioanalytical testing.