Used in research and development for inflammatory and autoimmune diseases, this antibody serves as a reference standard in bioassays to neutralize TNFα activity. It is employed in preclinical studies to evaluate the efficacy of anti-TNF therapies, particularly in models of rheumatoid arthritis, inflammatory bowel disease, and psoriasis. Due to its well-characterized binding properties, it helps calibrate assays measuring TNFα inhibition, ensuring consistency across experiments and therapeutic antibody development. It is also utilized in quality control during biosimilar development to benchmark functional performance against existing anti-TNF biologics.