Used in research and diagnostic applications to detect and quantify TNFα (tumor necrosis factor alpha), a key cytokine involved in systemic inflammation. This antibody is particularly valuable in immunoassays such as ELISA, Western blotting, and immunohistochemistry due to its high specificity and affinity for TNFα. It serves as a reference standard in studies related to autoimmune diseases like rheumatoid arthritis, Crohn’s disease, and psoriasis, helping evaluate the efficacy of anti-TNF therapies. Its role in neutralizing TNFα activity also supports functional studies in cell cultures and animal models of inflammation.