Used in the treatment of autoimmune diseases such as rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, and psoriatic arthritis. It works by neutralizing tumor necrosis factor-alpha (TNF-α), a key mediator of inflammation, thereby reducing inflammation, slowing disease progression, and improving symptoms. Due to its PEGylated structure and lack of Fc region, it has reduced immunogenicity and does not mediate complement-dependent cytotoxicity, making it suitable for long-term therapy. Employed both in clinical settings and as a reference standard in bioassays and drug development.