Used in cancer immunotherapy research to block the TGF-β1 signaling pathway, enhancing immune system activity against tumors. Investigated for its ability to promote T cell infiltration into tumor sites and improve the efficacy of checkpoint inhibitors. Applied in preclinical studies for solid tumors including lung, breast, and colorectal cancers. Also utilized as a reference standard in bioassays to evaluate neutralizing activity of other anti-TGF-β1 agents.