Used in targeted cancer therapies, particularly in blocking the TGF-β signaling pathway to inhibit tumor growth and metastasis. It is investigated for its role in enhancing immune response against solid tumors by modulating the tumor microenvironment. This antibody has shown promise in clinical trials for cancers such as colorectal, pancreatic, and non-small cell lung cancer. It is also utilized as a reference standard in bioanalytical assays to evaluate the performance of biosimilars and other anti-TGF-β antibodies.