Anti-STOP1 Reference Antibody (Genentech patent anti-STOP-1)
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Used in research and development for targeting STOP-1, a protein implicated in tumor immune evasion. This reference antibody serves as a critical tool in immuno-oncology studies, particularly in validating assays and characterizing the function of STOP-1 in immune cell regulation. It supports the development of therapeutic antibodies by providing a benchmark for binding affinity, specificity, and functional activity. Commonly employed in flow cytometry, immunohistochemistry, and in vitro functional assays to monitor target expression and modulation in preclinical models. Also utilized in pharmacokinetic and pharmacodynamic studies during early drug discovery to assess target engagement and biological response.
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