Used in research to target Siglec-15, a protein involved in immune regulation, particularly in the suppression of T-cell activity within the tumor microenvironment. This antibody serves as a reference tool for developing immunotherapies, especially in oncology, where blocking Siglec-15 may enhance anti-tumor immune responses. It is also employed in biomarker studies to evaluate Siglec-15 expression in diseased tissues, supporting the development of targeted cancer treatments. Additionally, it aids in the validation of diagnostic assays and therapeutic antibody candidates through binding and functional assays.