Used in targeted cancer therapies, particularly in melanoma treatment, due to its specific binding to PMEL17, a protein highly expressed in melanocytes and melanoma cells. This antibody serves as a key component in antibody-drug conjugates (ADCs), delivering cytotoxic agents directly to tumor cells while minimizing damage to healthy tissues. It is also utilized in diagnostic imaging to detect melanoma metastases. Its high specificity makes it valuable in research for studying melanin synthesis and melanocyte biology.