Used in the treatment of advanced melanoma, non-small cell lung cancer, and other solid tumors by enhancing the body's immune response against cancer cells. It works by blocking the PD-1 receptor on T-cells, preventing tumor cells from evading immune detection. This antibody helps restore T-cell activation and promotes durable anti-tumor responses. It is administered intravenously and is often used when other treatments have failed. Clinical trials have also explored its use in nasopharyngeal carcinoma, showing improved outcomes in certain patient populations.