Anti-PCSK9 Reference Antibody (evolocumab)
Reagent
Code: #140379
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-20℃
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Used in the treatment of high cholesterol, particularly in patients with familial hypercholesterolemia or a history of cardiovascular disease. It works by inhibiting PCSK9, a protein that reduces the liver's ability to remove low-density lipoprotein (LDL) cholesterol from the blood. By blocking PCSK9, this antibody increases LDL receptor recycling, leading to significantly lower LDL cholesterol levels. Administered via subcutaneous injection, it is often prescribed alongside statins or for patients who cannot tolerate statin therapy. Its use has been shown to reduce the risk of heart attack, stroke, and coronary revascularization in high-risk patients.
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