Used in research and therapeutic development targeting inflammatory and immune-mediated diseases. Specifically applied in studies involving chronic inflammation, asthma, atopic dermatitis, and certain cancers where PAR-2 (Protease-Activated Receptor 2) signaling plays a key role. Enables precise detection and modulation of PAR-2 activity in cellular and tissue models. Supports drug discovery by serving as a reference standard for evaluating efficacy and specificity of new anti-PAR-2 agents. Also utilized in preclinical models to validate target engagement and biological response.