Used in immunological research to detect and study MICB (MHC class I polypeptide-related sequence B) expression on stressed or infected cells. This antibody is instrumental in experiments involving immune cell activation, particularly in natural killer (NK) cell and T cell responses, due to MICB's role as a ligand for the NKG2D receptor. It supports flow cytometry, immunohistochemistry, and functional blocking assays to investigate immune surveillance, tumor immunity, and autoimmune diseases. Its use in academic and preclinical research helps elucidate mechanisms of immune recognition and supports development of immunotherapies.