Used in the treatment of rheumatoid arthritis to reduce inflammation and slow disease progression. Also applied in managing juvenile idiopathic arthritis and systemic sclerosis. Employed in cytokine release syndrome, including severe cases of COVID-19, to mitigate excessive immune response. Investigated for use in giant cell arteritis and other autoimmune conditions due to its ability to block interleukin-6 signaling. Administered intravenously or subcutaneously in clinical settings.