Used in the treatment of autoimmune and inflammatory diseases, particularly rheumatoid arthritis. It works by blocking the interleukin-1 receptor (IL-1R1), thereby inhibiting the pro-inflammatory effects of IL-1, a key cytokine involved in joint inflammation and tissue damage. This antibody helps reduce disease activity, slow cartilage destruction, and improve physical function in patients unresponsive to conventional therapies. It has also been investigated for use in other IL-1-mediated conditions such as osteoarthritis, ankylosing spondylitis, and certain skin disorders.