Anti-IGF1 Reference Antibody (xentuzumab)
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Anti-IGF1 Reference Antibody (xentuzumab) is used in molecular biology and biomedical research to study the role of insulin-like growth factor 1 (IGF-1), particularly in cell growth, proliferation, and survival processes. It serves as a reference standard in the development of therapeutic antibodies and for investigating IGF-1 signaling pathways associated with conditions such as diabetes, cancer, and muscle degeneration. This antibody can be employed to measure IGF-1 levels in biological samples using techniques like ELISA or Western blot analysis, helping to confirm target inhibition in experimental studies. As a research tool, it mimics the binding properties of xentuzumab, a monoclonal antibody under investigation in clinical trials for cancers including breast, prostate, and non-small cell lung cancer, but it is not intended for therapeutic use.
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