Used in research and development for allergic diseases, particularly in studies related to IgE-mediated pathways such as asthma and allergic rhinitis. Serves as a reference standard in immunoassays to measure anti-IgE antibody activity and binding affinity. Employed in quality control during the production of therapeutic antibodies targeting IgE. Also utilized in preclinical studies to evaluate mechanisms of mast cell and basophil activation inhibition.